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Structure and Dynamics of the Actin Filament

We used all-atom molecular dynamics simulations to investigate the structure and properties of the actin filament, starting with either the recent Oda model or the older Holmes model. Simulations of monomeric and polymerized actin show that polymerization changes the nucleotide-binding cleft, bringi...

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Autors principals: Pfaendtner, Jim, Lyman, Edward, Pollard, Thomas D., Voth, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815099/
https://ncbi.nlm.nih.gov/pubmed/19931282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.034
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