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Structure and Dynamics of the Actin Filament

We used all-atom molecular dynamics simulations to investigate the structure and properties of the actin filament, starting with either the recent Oda model or the older Holmes model. Simulations of monomeric and polymerized actin show that polymerization changes the nucleotide-binding cleft, bringi...

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Bibliografiske detaljer
Main Authors: Pfaendtner, Jim, Lyman, Edward, Pollard, Thomas D., Voth, Gregory A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2815099/
https://ncbi.nlm.nih.gov/pubmed/19931282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.11.034
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