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Key Structural Features of the Actin Filament Arp2/3 Complex Branch Junction Revealed by Molecular Simulation

We investigated the structure, properties and dynamics of the actin filament branch junction formed by Arp2/3 complex using all-atom molecular dynamics simulations based on a model fit to a reconstruction from electron tomograms. Simulations of the entire structure consisting of 31 protein subunits...

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Detalhes bibliográficos
Main Authors: Pfaendtner, Jim, Volkmann, Niels, Hanein, Dorit, Dalhaimer, Paul, Pollard, Thomas D., Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423189/
https://ncbi.nlm.nih.gov/pubmed/22206989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.025
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