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Mechanism of Filament Nucleation and Branch Stability Revealed by the Structure of the Arp2/3 Complex at Actin Branch Junctions

Actin branch junctions are conserved cytoskeletal elements critical for the generation of protrusive force during actin polymerization-driven cellular motility. Assembly of actin branch junctions requires the Arp2/3 complex, upon activation, to initiate a new actin (daughter) filament branch from th...

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Autors principals: Egile, Coumaran, Rouiller, Isabelle, Xu, Xiao-Ping, Volkmann, Niels, Li, Rong, Hanein, Dorit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1278936/
https://ncbi.nlm.nih.gov/pubmed/16262445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030383
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