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An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability
The Arp2/3 complex polymerizes new actin filaments from the sides of existing filaments, forming Y-branched networks that are critical for actin-mediated force generation. Binding of the Arp2/3 complex to the sides of actin filaments is therefore central to its actin-nucleating and branching activit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889539/ https://ncbi.nlm.nih.gov/pubmed/20404198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911668107 |
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