Nucleotide-dependent conformational states of actin

The influence of the state of the bound nucleotide (ATP, ADP-Pi, or ADP) on the conformational free-energy landscape of actin is investigated. Nucleotide-dependent folding of the DNase-I binding (DB) loop in monomeric actin and the actin trimer is carried out using all-atom molecular dynamics (MD) c...

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Detaylı Bibliyografya
Asıl Yazarlar: Pfaendtner, Jim, Branduardi, Davide, Parrinello, Michele, Pollard, Thomas D., Voth, Gregory A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2009
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2722336/
https://ncbi.nlm.nih.gov/pubmed/19620726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902092106
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