A novel mouse model for the aggressive variant of NK cell and T cell large granular lymphocyte leukemia

Murine models of disease are vital to the understanding of pathogenesis and the development of novel therapeutics. We have previously established interleukin (IL)-15 transgenic (tg) mice that demonstrate rapid proliferation of natural killer (NK) and T cells, followed by spontaneous transformation t...

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Autori principali: Yokohama, Akihiko, Mishra, Anjali, Mitsui, Takeki, Becknell, Brian, Johns, Jessica, Curphey, Douglas, Blaser, Bradley W., VanDeusen, Jeffrey B., Mao, Hsiaoyin, Yu, Jianhua, Caligiuri, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814907/
https://ncbi.nlm.nih.gov/pubmed/19660811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2009.06.031
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