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Evidence for discrete stages of human natural killer cell differentiation in vivo

Human natural killer (NK) cells originate from CD34(+) hematopoietic progenitor cells, but the discrete stages of NK cell differentiation in vivo have not been elucidated. We identify and functionally characterize, from human lymph nodes and tonsils, four NK cell developmental intermediates spanning...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Freud, Aharon G., Yokohama, Akihiko, Becknell, Brian, Lee, Melissa T., Mao, Hsiaoyin C., Ferketich, Amy K., Caligiuri, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118285/
https://ncbi.nlm.nih.gov/pubmed/16606675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052507
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