Stem cell factor and interleukin-2/15 combine to enhance MAPK-mediated proliferation of human natural killer cells

Stem cell factor (SCF) promotes synergistic cellular proliferation in combination with several growth factors, and appears important for normal natural killer (NK)–cell development. CD34(+) hematopoietic precursor cells (HPCs) require interleukin-15 (IL-15) for differentiation into human NK cells, a...

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Detalhes bibliográficos
Main Authors: Benson, Don M., Yu, Jianhua, Becknell, Brian, Wei, Min, Freud, Aharon G., Ferketich, Amy K., Trotta, Rossana, Perrotti, Danilo, Briesewitz, Roger, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661858/
https://ncbi.nlm.nih.gov/pubmed/19060242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-159285
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