Hlx homeobox transcription factor negatively regulates interferon-γ production in monokine-activated natural killer cells

Natural killer (NK) cells contribute to host immunity, including tumor surveillance, through the production of interferon gamma (IFN-γ). Although there is some knowledge about molecular mechanisms that induce IFN-γ in NK cells, considerably less is known about the mechanisms that reduce its expressi...

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Auteurs principaux: Becknell, Brian, Hughes, Tiffany L., Freud, Aharon G., Blaser, Bradley W., Yu, Jianhua, Trotta, Rossana, Mao, Hsiaoyin C., Caligiuri de Jesús, Marie L., Alghothani, Mohamad, Benson, Don M., Lehman, Amy, Jarjoura, David, Perrotti, Danilo, Bates, Michael D., Caligiuri, Michael A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2007
Sujets:
Immunobiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852195/
https://ncbi.nlm.nih.gov/pubmed/17110450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-10-050096
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