The PP2A inhibitor SET regulates natural killer cell IFN-γ production

Monokines (i.e., interleukin [IL]-12, -18, and -15) induce natural killer (NK) cells to produce interferon-γ (IFN-γ), which is a critical factor for immune surveillance of cancer and monocyte clearance of infection. We show that SET, which is a potent inhibitor of protein phosphatase type 2A (PP2A)...

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Detalhes bibliográficos
Main Authors: Trotta, Rossana, Ciarlariello, David, Col, Jessica Dal, Allard, Jeffrey, Neviani, Paolo, Santhanam, Ramasamy, Mao, Hsiaoyin, Becknell, Brian, Yu, Jianhua, Ferketich, Amy K., Thomas, Brittany, Modi, Aalok, Blaser, Bradley W., Perrotti, Danilo, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118465/
https://ncbi.nlm.nih.gov/pubmed/17875674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070419
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