NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human

IL-15 may have a role in the development of T cell large granular lymphocyte (T-LGL) or NKT leukemias. However, the mechanisms of action and the identity of the cell subset that undergoes leukemic transformation remain elusive. Here we show that in both mice and humans, NKp46 expression marks a minu...

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Bibliografiska uppgifter
Huvudupphovsmän: Yu, Jianhua, Mitsui, Takeki, Wei, Min, Mao, Hsiaoyin, Butchar, Jonathan P., Shah, Mithun Vinod, Zhang, Jianying, Mishra, Anjali, Alvarez-Breckenridge, Christopher, Liu, Xingluo, Liu, Shujun, Yokohama, Akihiko, Trotta, Rossana, Marcucci, Guido, Benson, Don M., Loughran, Thomas P., Tridandapani, Susheela, Caligiuri, Michael A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069763/
https://ncbi.nlm.nih.gov/pubmed/21364281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43242
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