NKp46 identifies an NKT cell subset susceptible to leukemic transformation in mouse and human

IL-15 may have a role in the development of T cell large granular lymphocyte (T-LGL) or NKT leukemias. However, the mechanisms of action and the identity of the cell subset that undergoes leukemic transformation remain elusive. Here we show that in both mice and humans, NKp46 expression marks a minu...

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Detalhes bibliográficos
Main Authors: Yu, Jianhua, Mitsui, Takeki, Wei, Min, Mao, Hsiaoyin, Butchar, Jonathan P., Shah, Mithun Vinod, Zhang, Jianying, Mishra, Anjali, Alvarez-Breckenridge, Christopher, Liu, Xingluo, Liu, Shujun, Yokohama, Akihiko, Trotta, Rossana, Marcucci, Guido, Benson, Don M., Loughran, Thomas P., Tridandapani, Susheela, Caligiuri, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069763/
https://ncbi.nlm.nih.gov/pubmed/21364281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43242
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