In Vivo Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists [(11)C]A-582941 and [(11)C]A-844606 in Mice and Conscious Monkeys

BACKGROUND: The α7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. The goal of this study was to evaluate the two carbon-11-labeled α7 nAChR agonists [(11)C]A-582941 and [(11)C]A...

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Detaylı Bibliyografya
Asıl Yazarlar: Toyohara, Jun, Ishiwata, Kiichi, Sakata, Muneyuki, Wu, Jin, Nishiyama, Shingo, Tsukada, Hideo, Hashimoto, Kenji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813863/
https://ncbi.nlm.nih.gov/pubmed/20126539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008961
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