Reduction of dopamine D(2/3) receptor binding in the striatum after a single administration of esketamine, but not R-ketamine: a PET study in conscious monkeys

R-ketamine appears to be a potent, long-lasting and safer antidepressant, relative to esketamine (S-ketamine), since it might be free of psychotomimetic side effects. Using [(11)C]raclopride and positron emission tomography (PET), we investigated whether esketamine and R-ketamine can affect dopamine...

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Vydáno v:Eur Arch Psychiatry Clin Neurosci
Hlavní autoři: Hashimoto, Kenji, Kakiuchi, Takeharu, Ohba, Hiroyuki, Nishiyama, Shingo, Tsukada, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323469/
https://ncbi.nlm.nih.gov/pubmed/27091456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00406-016-0692-7
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