Subanesthetic Doses of Ketamine Transiently Decrease Serotonin Transporter Activity: A PET Study in Conscious Monkeys

Subanesthetic doses of ketamine, an N-methyl-D-aspartic acid (NMDA) antagonist, have a rapid antidepressant effect which lasts for up to 2 weeks. However, the neurobiological mechanism regarding this effect remains unclear. In the present study, the effects of subanesthetic doses of ketamine on sero...

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Detalhes bibliográficos
Main Authors: Yamamoto, Shigeyuki, Ohba, Hiroyuki, Nishiyama, Shingo, Harada, Norihiro, Kakiuchi, Takeharu, Tsukada, Hideo, Domino, Edward F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828538/
https://ncbi.nlm.nih.gov/pubmed/23880871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.176
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