[(11)C]CHIBA-1001 as a Novel PET Ligand for α7 Nicotinic Receptors in the Brain: A PET Study in Conscious Monkeys

BACKGROUND: The α7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. However, there are currently no suitable positron emission tomography (PET) radioligands for imaging α7 nAChRs...

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Hlavní autoři: Hashimoto, Kenji, Nishiyama, Shingo, Ohba, Hiroyuki, Matsuo, Masaaki, Kobashi, Tatsuhiko, Takahagi, Makoto, Iyo, Masaomi, Kitashoji, Takeru, Tsukada, Hideo
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2008
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529405/
https://ncbi.nlm.nih.gov/pubmed/18800169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003231
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