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E2F2 Suppresses Myc-induced Proliferation and Tumorigenesis

Deregulation of E2F transcriptional activity as a result of alterations in the p16-cyclin D-Rb pathway is a hallmark of cancer. However, the roles of the different E2F family members in the process of tumorigenesis are still being elucidated. Studies in mice and humans suggest that E2F2 functions as...

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Main Authors: Pusapati, Raju V., Weaks, Regina L., Rounbehler, Robert J., McArthur, Mark J., Johnson, David G.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813383/
https://ncbi.nlm.nih.gov/pubmed/19798698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20584
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