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ATM promotes apoptosis and suppresses tumorigenesis in response to Myc
Overexpression of the c-myc oncogene contributes to the development of a significant number of human cancers. In response to deregulated Myc activity, the p53 tumor suppressor is activated to promote apoptosis and inhibit tumor formation. Here we demonstrate that p53 induction in response to Myc ove...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1345703/ https://ncbi.nlm.nih.gov/pubmed/16432227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507367103 |
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