ATM promotes apoptosis and suppresses tumorigenesis in response to Myc

Overexpression of the c-myc oncogene contributes to the development of a significant number of human cancers. In response to deregulated Myc activity, the p53 tumor suppressor is activated to promote apoptosis and inhibit tumor formation. Here we demonstrate that p53 induction in response to Myc ove...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pusapati, Raju V., Rounbehler, Robert J., Hong, SungKi, Powers, John T., Yan, Mingshan, Kiguchi, Kaoru, McArthur, Mark J., Wong, Paul K., Johnson, David G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2006
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1345703/
https://ncbi.nlm.nih.gov/pubmed/16432227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507367103
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak