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The Myc 3′ Wnt-Responsive Element Suppresses Colonic Tumorigenesis

Mutations in components of the Wnt/β-catenin signaling pathway are commonly found in colorectal cancers, and these mutations cause aberrant expression of genes controlled by Wnt-responsive DNA elements (WREs). While the c-Myc proto-oncogene (Myc) is required for intestinal phenotypes associated with...

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Autori principali: Konsavage, Wesley M., Yochum, Gregory S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993608/
https://ncbi.nlm.nih.gov/pubmed/24567369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00969-13
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