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The Myc 3′ Wnt-Responsive Element Suppresses Colonic Tumorigenesis
Mutations in components of the Wnt/β-catenin signaling pathway are commonly found in colorectal cancers, and these mutations cause aberrant expression of genes controlled by Wnt-responsive DNA elements (WREs). While the c-Myc proto-oncogene (Myc) is required for intestinal phenotypes associated with...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993608/ https://ncbi.nlm.nih.gov/pubmed/24567369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00969-13 |
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