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Total Synthesis of (−)-Platensimycin, a Novel Antibacterial Agent
An enantioselective synthesis of platensimycin, a novel antibiotic natural product that inhibits bacterial β-ketoacyl-(acyl-carrier-protein) synthase (FabF), is described. Our synthetic strategy for the construction of the oxatetracyclic core involved an intramolecular Diels-Alder reaction. Our prel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812928/ https://ncbi.nlm.nih.gov/pubmed/19123842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo802261f |
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