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A Symmetry-based, Concise Formal Synthesis of Platencin, a Novel Lead against ‘Superbugs’

The quick access: A concise and efficient formal synthesis of platencin has been accomplished in 9 steps from a commercially available starting material. The synthesis utilized only one protecting group. The base catalyzed Michael cyclization of precursor 1 afforded the key diketone 2, which was con...

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Detalhes bibliográficos
Main Authors: Ghosh, Arun K., Xi, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518310/
https://ncbi.nlm.nih.gov/pubmed/19572306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200902338
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