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Short Enantioselective Formal Synthesis of (−)-Platencin

A short enantioselective formal synthesis of the antibiotic natural product platencin is reported. Key steps in the synthesis include enantioselective decarboxylation alkylation, aldehyde/olefin radical cyclization, and regioselective aldol cyclization.

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Detalhes bibliográficos
Publicado no:Synthesis (Stuttg)
Main Authors: Defieber, Christian, Mohr, Justin T., Grabovyi, Gennadii A., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498846/
https://ncbi.nlm.nih.gov/pubmed/31061542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1610437
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