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Enantioselective Protonation

Enantioselective protonation is a common process in biosynthetic sequences. The decarboxylase and esterase enzymes that effect this valuable transformation are able to control both the steric environment around the proton acceptor (typically an enolate) and the proton donor (typically a thiol). Rece...

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Detalles Bibliográficos
Main Authors: Mohr, Justin T., Hong, Allen Y., Stoltz, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860147/
https://ncbi.nlm.nih.gov/pubmed/20428461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.297
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