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Enantioselective Protonation

Enantioselective protonation is a common process in biosynthetic sequences. The decarboxylase and esterase enzymes that effect this valuable transformation are able to control both the steric environment around the proton acceptor (typically an enolate) and the proton donor (typically a thiol). Rece...

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Dettagli Bibliografici
Autori principali: Mohr, Justin T., Hong, Allen Y., Stoltz, Brian M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2860147/
https://ncbi.nlm.nih.gov/pubmed/20428461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.297
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