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Synthesis and Antibacterial Properties of (–)-nor-Platencin

[Image: see text] An asymmetric Diels–Alder reaction between acrolein and 1-benzyloxymethyl-1,3-cyclohexadiene affords a bicyclic aldehyde that was elaborated in 11 steps to nor-platencin. nor-Platencin is 4–16 times less active than platencin against several resistant strains of Staphylococcus aure...

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Detalhes bibliográficos
Main Authors: Barykina, Olga V., Rossi, Kerri L., Rybak, Michael J., Snider, Barry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789445/
https://ncbi.nlm.nih.gov/pubmed/19845392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902194q
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