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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning
Lymphocyte egress from lymph nodes (LNs) is dependent on sphingosine-1-phosphate (S1P), but the cellular source of this S1P is not defined. We generated mice that expressed Cre from the lymphatic vessel endothelial hyaluronan receptor 1 (Lyve-1) locus and that showed efficient recombination of loxP-...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812554/ https://ncbi.nlm.nih.gov/pubmed/20026661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091619 |
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