Cortical sinus probing, S1P(1)-dependent entry and flow-based capture of egressing T cells

The cellular dynamics of lymphocyte egress from lymph nodes are poorly defined. Here, we visualized the branched organization of lymph node cortical sinuses and found that after entry some T cells were retained while others returned to the parenchyma. Sphingosine-1-phosphate receptor 1 (S1P(1))-defi...

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Bibliographic Details
Main Authors: Grigorova, Irina L, Schwab, Susan R, Phan, Tri Giang, Pham, Trung H M, Okada, Takaharu, Cyster, Jason G
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710451/
https://ncbi.nlm.nih.gov/pubmed/19060900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1682
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