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Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure

Recent studies have identified cortical sinuses as sites of sphingosine-1-phosphate receptor-1 (S1P(1))-dependent T- and B-cell egress from the lymph node (LN) parenchyma. However, the distribution of cortical sinuses in the entire LN and the extent of lymph flow within them has been unclear. Using...

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Bibliografiske detaljer
Main Authors: Grigorova, Irina L., Panteleev, Mikhail, Cyster, Jason G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996652/
https://ncbi.nlm.nih.gov/pubmed/21059923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009968107
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