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A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes
Lymphocytes use the integrin leukocyte function-associated antigen-1 (LFA-1) to cross the vasculature into lymph nodes (LNs), but it has been uncertain whether their migration within LN is also LFA-1 dependent. We show that LFA-1 mediates prolonged LN residence as LFA-1(−/−) CD4 T cells have signifi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
European Molecular Biology Organization
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3604724/ https://ncbi.nlm.nih.gov/pubmed/23443048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.33 |
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