Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

Maintenance of vascular integrity is critical for homeostasis, and temporally and spatially regulated vascular leak is a central feature of inflammation. Sphingosine-1-phosphate (S1P) can regulate endothelial barrier function, but the sources of the S1P that provide this activity in vivo and its imp...

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Detalhes bibliográficos
Main Authors: Camerer, Eric, Regard, Jean B., Cornelissen, Ivo, Srinivasan, Yoga, Duong, Daniel N., Palmer, Daniel, Pham, Trung H., Wong, Jinny S., Pappu, Rajita, Coughlin, Shaun R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701879/
https://ncbi.nlm.nih.gov/pubmed/19603543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38575
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