Local Protease Signaling Contributes to Neural Tube Closure in the Mouse Embryo

We report an unexpected role for protease signaling in neural tube closure and formation of the central nervous system. Mouse embryos lacking protease-activated receptor 1 and 2 showed defective hindbrain and posterior neuropore closure and developed exencephaly and spina bifida, important human con...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Camerer, Eric, Barker, Adrian, Duong, Daniel N., Ganesan, Rajkumar, Kataoka, Hiroshi, Cornelissen, Ivo, Darragh, Molly R., Hussain, Arif, Zheng, Yao-Wu, Srinivasan, Yoga, Brown, Christopher, Xu, Shan-Mei, Regard, Jean B., Lin, Chen-Yong, Craik, Charles S., Kirchhofer, Daniel, Coughlin, Shaun R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822780/
https://ncbi.nlm.nih.gov/pubmed/20152175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.11.014
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge