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Redundancy and interaction of thrombin- and collagen-mediated platelet activation in tail bleeding and carotid thrombosis in mice

OBJECTIVE: Current antiplatelet strategies to prevent myocardial infarction and stroke are limited by bleeding risk. A better understanding of the roles of distinct platelet-activating pathways is needed. We determined whether platelet activation by two key primary activators, thrombin and collagen,...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Bynagari-Settipalli, Yamini S., Cornelissen, Ivo, Palmer, Daniel, Duong, Daniel, Concengco, Cherry, Ware, Jerry, Coughlin, Shaun R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239193/
https://ncbi.nlm.nih.gov/pubmed/25278288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304244
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