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Roles and interactions among protease-activated receptors and P2ry12 in hemostasis and thrombosis

Toward understanding their redundancies and interactions in hemostasis and thrombosis, we examined the roles of thrombin receptors (protease-activated receptors, PARs) and the ADP receptor P2RY12 (purinergic receptor P2Y G protein-coupled 12) in human and mouse platelets ex vivo and in mouse models....

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Autores principales: Cornelissen, Ivo, Palmer, Daniel, David, Tovo, Wilsbacher, Lisa, Concengco, Cherry, Conley, Pamela, Pandey, Anjali, Coughlin, Shaun R.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972928/
https://ncbi.nlm.nih.gov/pubmed/20930120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013309107
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