Generation of PLZF(+) CD4(+) T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans

Human thymocytes, unlike mouse thymocytes, express major histocompatibility complex (MHC) class II molecules on their surface, especially during the fetal and perinatal stages. Based on this observation, we previously identified a novel developmental pathway for the generation of CD4(+) T cells via...

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Main Authors: Lee, You Jeong, Jeon, Yoon Kyung, Kang, Byung Hyun, Chung, Doo Hyun, Park, Chung-Gyu, Shin, Hee Young, Jung, Kyeong Cheon, Park, Seong Hoe
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812550/
https://ncbi.nlm.nih.gov/pubmed/20038602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091519
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