CD4(+) T cells from MHC II-dependent thymocyte–thymocyte interaction provide efficient help for B cells

Recently, a novel CD4(+) T-cell developmental pathway was reported that generates thymocyte–thymocyte (T–T) CD4(+) T cells. We established a mouse system (CIITA(tg)CIITApIV(−/−)) where thymic positive selection occurred only by major histocompatibility complex (MHC) class II(+) thymocytes. T–T CD4(+...

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Detalhes bibliográficos
Main Authors: Kim, Eun Ji, Choi, Bomi, Moon, Hana, Lee, You Jeong, Jeon, Yoon Kyeong, Park, Seong Hoe, Kim, Tae Jin, Jung, Kyeong Cheon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257047/
https://ncbi.nlm.nih.gov/pubmed/21358747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2011.8
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