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Generation of PLZF(+) CD4(+) T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans
Human thymocytes, unlike mouse thymocytes, express major histocompatibility complex (MHC) class II molecules on their surface, especially during the fetal and perinatal stages. Based on this observation, we previously identified a novel developmental pathway for the generation of CD4(+) T cells via...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812550/ https://ncbi.nlm.nih.gov/pubmed/20038602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091519 |
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