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Generation of PLZF(+) CD4(+) T cells via MHC class II–dependent thymocyte–thymocyte interaction is a physiological process in humans

Human thymocytes, unlike mouse thymocytes, express major histocompatibility complex (MHC) class II molecules on their surface, especially during the fetal and perinatal stages. Based on this observation, we previously identified a novel developmental pathway for the generation of CD4(+) T cells via...

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Hlavní autoři: Lee, You Jeong, Jeon, Yoon Kyung, Kang, Byung Hyun, Chung, Doo Hyun, Park, Chung-Gyu, Shin, Hee Young, Jung, Kyeong Cheon, Park, Seong Hoe
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812550/
https://ncbi.nlm.nih.gov/pubmed/20038602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091519
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