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Interaction between the mouse homologue of CD99 and its ligand PILR as a mechanism of T cell receptor-independent thymocyte apoptosis

Here, we show that the interaction between two membrane proteins, the mouse homologue of CD99 (designated D4) and its ligand, paired immunoglobulin-like type 2 receptor (PILR), is one of the major mechanisms of thymocyte apoptosis. Using the polymeric fusion protein of PILR and IgG1 (PILR-Ig), we de...

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Autores principales: Park, Hyo Jin, Ban, Young Larn, Byun, Dahye, Park, Seong Hoe, Jung, Kyeong Cheon
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Society for Biochemistry and Molecular Biology 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877249/
https://ncbi.nlm.nih.gov/pubmed/20208422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.5.037
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