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Kinetics of PIP(2) metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
The signaling phosphoinositide phosphatidylinositol 4,5-bisphosphate (PIP(2)) is synthesized in two steps from phosphatidylinositol by lipid kinases. It then interacts with KCNQ channels and with pleckstrin homology (PH) domains among many other physiological protein targets. We measured and develop...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812502/ https://ncbi.nlm.nih.gov/pubmed/20100891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910345 |
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