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Kinetics of M(1) muscarinic receptor and G protein signaling to phospholipase C in living cells

G protein–coupled receptors (GPCRs) mediate responses to external stimuli in various cell types. Early events, such as the binding of ligand and G proteins to the receptor, nucleotide exchange (NX), and GTPase activity at the Gα subunit, are common for many different GPCRs. For G(q)-coupled M(1) mus...

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Autors principals: Falkenburger, Björn H., Jensen, Jill B., Hille, Bertil
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812500/
https://ncbi.nlm.nih.gov/pubmed/20100890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910344
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