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Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signaling
G(q) protein–coupled receptors (G(q)PCRs) of the plasma membrane activate the phospholipase C (PLC) signaling cascade. PLC cleaves the membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP(2)) into the second messengers diacylgycerol (DAG) and inositol 1,4,5-trisphosphate (IP(3)), leading to cal...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3639584/ https://ncbi.nlm.nih.gov/pubmed/23630338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210887 |
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