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The cannabinoid agonist WIN55,212-2 increases intracellular calcium via CB(1) receptor coupling to G(q/11) G proteins
Central nervous system responses to cannabis are primarily mediated by CB(1) receptors, which couple preferentially to G(i/o) G proteins. Here, we used calcium photometry to monitor the effect of CB(1) activation on intracellular calcium concentration. Perfusion with 5 μM CB(1) aminoalkylindole agon...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1323208/ https://ncbi.nlm.nih.gov/pubmed/16365309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509588102 |
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