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Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers
G protein-coupled receptors (GPCRs) transmit signals by forming active-state complexes with heterotrimeric G proteins. It has been suggested that some GPCRs also assemble with G proteins prior to ligand-induced activation, and that inactive-state preassembly facilitates rapid and specific G protein...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177959/ https://ncbi.nlm.nih.gov/pubmed/21873996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.642 |
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