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Differential dissociation of G protein heterotrimers

Signalling by heterotrimeric G proteins is often isoform-specific, meaning certain effectors are regulated exclusively by one family of heterotrimers. For example, in excitable cells inwardly rectifying potassium (GIRK) channels are activated by Gβγ dimers derived specifically from G(i/o) heterotrim...

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Autors principals: Digby, Gregory J, Sethi, Pooja R, Lambert, Nevin A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538816/
https://ncbi.nlm.nih.gov/pubmed/18499725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.153965
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