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Membrane-localized β-subunits alter the PIP(2) regulation of high-voltage activated Ca(2+) channels

The β-subunits of voltage-gated Ca(2+) (Ca(V)) channels regulate the functional expression and several biophysical properties of high-voltage–activated Ca(V) channels. We find that Ca(V) β-subunits also determine channel regulation by the membrane phospholipid phosphatidylinositol 4,5-bisphosphate (...

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Detalhes bibliográficos
Main Authors: Suh, Byung-Chang, Kim, Dong-Il, Falkenburger, Björn H., Hille, Bertil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287006/
https://ncbi.nlm.nih.gov/pubmed/22308488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121434109
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