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Translocatable voltage-gated Ca(2+) channel β subunits in α1–β complexes reveal competitive replacement yet no spontaneous dissociation

β subunits of high voltage-gated Ca(2+) (Ca(V)) channels promote cell-surface expression of pore-forming α1 subunits and regulate channel gating through binding to the α-interaction domain (AID) in the first intracellular loop. We addressed the stability of Ca(V) α1B–β interactions by rapamycin-tran...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Yeon, Jun-Hee, Park, Cheon-Gyu, Hille, Bertil, Suh, Byung-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196550/
https://ncbi.nlm.nih.gov/pubmed/30257950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1809762115
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