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Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans Induces DNA Damage, S/G(2) Cell Cycle Arrest, and Caspase- Independent Death in a Saccharomyces cerevisiae Model
Cytolethal distending toxin (CDT) is a bacterial toxin that induces G(2)/M cell cycle arrest, cell distension, and/or apoptosis in mammalian cells. It is produced by several Gram-negative species and may contribute to their pathogenicity. The catalytic subunit CdtB has homology with DNase I and may...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812194/ https://ncbi.nlm.nih.gov/pubmed/19995894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00857-09 |
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