Host Chromatin Regulators Required for Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Activity in Saccharomyces cerevisiae Model

Cytolethal distending toxin (CDT) is a bacterial genotoxin that causes host cell cycle arrest and death. We previously employed a Saccharomyces cerevisiae model with inducible expression of the CDT catalytic subunit from Aggregatibacter actinomycetemcomitans, AaCdtB, and showed that a wide variety o...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Denmongkholchai, Siriyod, Tsuruda, Keiko, Sugai, Motoyuki, Mongkolsuk, Skorn, Matangkasombut, Oranart
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281284/
https://ncbi.nlm.nih.gov/pubmed/33941581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00036-21
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