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CdtC-Induced Processing of Membrane-Bound CdtA Is a Crucial Step in Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Holotoxin Formation

Aggregatibacter actinomycetemcomitans is an oral pathogen causing periodontal disease and bacterial endocarditis. It produces cytolethal distending toxin (CDT) that could damage mammalian cells and tissues. CDT is a tripartite protein toxin composed of CdtA, CdtB, and CdtC. We have previously indica...

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Podrobná bibliografie
Vydáno v:Infect Immun
Hlavní autoři: Tsuruda, Keiko, Matangkasombut, Oranart, Ohara, Masaru, Sugai, Motoyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820955/
https://ncbi.nlm.nih.gov/pubmed/29229729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00731-17
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