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A Comparison of the Roles of Peroxisome Proliferator-Activated Receptor and Retinoic Acid Receptor on CYP26 Regulation

The cytochrome P450 26 family is believed to be responsible for all-trans-retinoic acid (atRA) metabolism and elimination in the human fetus and adults. CYP26A1 and CYP26B1 mRNA is expressed in a tissue-specific manner, and mice in which the CPY26 isoform has been knocked out show distinct malformat...

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Hlavní autoři: Tay, Suzanne, Dickmann, Leslie, Dixit, Vaishali, Isoherranen, Nina
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812069/
https://ncbi.nlm.nih.gov/pubmed/19884280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.059071
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